Streamlined One-Pot Synthesis of Nitro Fatty Acids

  • A novel method for the synthesis of nitro fatty acids (NFAs), an intriguing class of endogenously occurring lipid mediators, is reported. This one-pot procedure enables the controlled and stereoselective construction of nitro fatty acids from a simple set of common building blocks in a highly facile manner. Thereby, this methodology offers a streamlined, highly modular access to naturally occurring nitro fatty acids as well as non-natural NFA derivatives.

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Author:Mohamed Hassan, Sara-Cathrin Krieg, Cedric Ndefo Nde, Jessica Roos, Thorsten J. Maier, Eman A. El Rady, Mohamed A. Raslan, Kamal U. Sadek, Georg ManolikakesORCiD
URN:urn:nbn:de:hbz:386-kluedo-80511
DOI:https://doi.org/10.1002/ejoc.202100247
ISSN:1099-0690
Parent Title (English):European Journal of Organic Chemistry
Publisher:Wiley
Document Type:Article
Language of publication:English
Date of Publication (online):2024/04/16
Year of first Publication:2021
Publishing Institution:Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau
Date of the Publication (Server):2024/04/16
Issue:2021/15
Page Number:14
First Page:2239
Last Page:2252
Source:https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.202100247
Faculties / Organisational entities:Kaiserslautern - Fachbereich Chemie
DDC-Cassification:5 Naturwissenschaften und Mathematik / 540 Chemie
Collections:Open-Access-Publikationsfonds
Licence (German):Zweitveröffentlichung