Efficient algorithms for Asymmetric Flow Field Flow Fractionation

  • This thesis is devoted to the modeling and simulation of Asymmetric Flow Field Flow Fractionation, which is a technique for separating particles of submicron scale. This process is a part of large family of Field Flow Fractionation techniques and has a very broad range of industrial applications, e. g. in microbiology, chemistry, pharmaceutics, environmental analysis. Mathematical modeling is crucial for this process, as due to the own nature of the process, lab ex- periments are difficult and expensive to perform. On the other hand, there are several challenges for the mathematical modeling: huge dominance (up to 106 times) of the flow over the diffusion, highly stretched geometry of the device. This work is devoted to developing fast and efficient algorithms, which take into the account the challenges, posed by the application, and provide reliable approximations for the quantities of interest. We present a new Multilevel Monte Carlo method for estimating the distribution functions on a compact interval, which are of the main interest for Asymmetric Flow Field Flow Fractionation. Error estimates for this method in terms of computational cost are also derived. We optimize the flow control at the Focusing stage under the given constraints on the flow and present an important ingredients for the further optimization, such as two-grid Reduced Basis method, specially adapted for the Finite Volume discretization approach.

Volltext Dateien herunterladen

Metadaten exportieren

Weitere Dienste

Teilen auf Twitter Suche bei Google Scholar
Verfasserangaben:Tigran Nagapetyan
URN (Permalink):urn:nbn:de:hbz:386-kluedo-38116
Betreuer:Oleg Iliev
Sprache der Veröffentlichung:Englisch
Veröffentlichungsdatum (online):06.03.2014
Jahr der Veröffentlichung:2014
Veröffentlichende Institution:Technische Universität Kaiserslautern
Titel verleihende Institution:Technische Universität Kaiserslautern
Datum der Annahme der Abschlussarbeit:02.11.2013
Datum der Publikation (Server):04.06.2014
Seitenzahl:VIII, 104 S.
Fachbereiche / Organisatorische Einheiten:Fachbereich Mathematik
DDC-Sachgruppen:5 Naturwissenschaften und Mathematik / 510 Mathematik
Lizenz (Deutsch):Standard gemäß KLUEDO-Leitlinien vom 10.09.2012