Two Simple and Highly Efficient Variants of the Griffith-Ley Oxidation of Alcohols
- The Griffith-Ley oxidation of alcohols to aldehydes and ketones is performed with either RuCl3 ⋅ (H2O)x or a highly stable, well-defined ruthenium catalyst and with cheap trimethylamine N-oxide (TMAO) as the oxygen source. The use of n-heptane as the solvent, which forms a second phase with TMAO and a part of the alcohol, allows the reactions to be performed with a minimum amount of catalyst. This results in high local concentrations and thus to very rapid conversions. Detailed quantum chemical calculations suggest, that the Griffith-Ley oxidation not necessarily requires high oxidation states of ruthenium but can also proceed with RuII/RuIV species.
Author: | Pascal Weingart, Patrick Hütchen, Angelo DamoneORCiD, Maximilian Kohns, Hans HasseORCiD, Werner R. ThielORCiD |
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URN: | urn:nbn:de:hbz:386-kluedo-80072 |
DOI: | https://doi.org/10.1002/cctc.202000413 |
ISSN: | 1867-3899 |
Parent Title (English): | ChemCatChem |
Publisher: | Wiley |
Document Type: | Article |
Language of publication: | English |
Date of Publication (online): | 2024/04/12 |
Year of first Publication: | 2020 |
Publishing Institution: | Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau |
Date of the Publication (Server): | 2024/04/12 |
Issue: | 12/15 |
Page Number: | 10 |
First Page: | 3919 |
Last Page: | 3928 |
Source: | https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cctc.202000413 |
Faculties / Organisational entities: | Kaiserslautern - Fachbereich Chemie |
DDC-Cassification: | 5 Naturwissenschaften und Mathematik / 540 Chemie |
Collections: | Open-Access-Publikationsfonds |
Licence (German): | Zweitveröffentlichung |