Palladium-Catalyzed Decarboxylative Three-Component Synthesis of α-Arylglycines: Replacing Boronic with Carboxylic Acids in the Petasis Reaction
- A palladium-catalyzed three-component synthesis of α-arylglycines from benzoic acids, sulfonamides and glyoxylic acid is reported. This novel reaction offers straightforward access to the important arylglycine motif in good yields and high structural diversity. By replacing boronic with carboxylic acids as nucleophilic component, this method can be considered as a more sustainable version of the classical Petasis reaction for synthesis of arylglycines.
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| Author: | Andreas M. Diehl, Georg ManolikakesORCiD |
|---|---|
| URN: | urn:nbn:de:hbz:386-kluedo-79970 |
| DOI: | https://doi.org/10.1002/cctc.202000652 |
| ISSN: | 1867-3899 |
| Parent Title (English): | ChemCatChem |
| Publisher: | Wiley |
| Document Type: | Article |
| Language of publication: | English |
| Date of Publication (online): | 2024/04/11 |
| Year of first Publication: | 2020 |
| Publishing Institution: | Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau |
| Date of the Publication (Server): | 2024/04/11 |
| Issue: | 12/13 |
| Page Number: | 4 |
| First Page: | 3463 |
| Last Page: | 3466 |
| Source: | https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cctc.202000652 |
| Faculties / Organisational entities: | Kaiserslautern - Fachbereich Chemie |
| DDC-Cassification: | 5 Naturwissenschaften und Mathematik / 540 Chemie |
| Collections: | Open-Access-Publikationsfonds |
| Licence (German): | Zweitveröffentlichung |