Due to remarkable technological advances in the last three decades the capacity of computer systems has improved tremendously. Considering Moore's law, the number of transistors on integrated circuits has doubled approximately every two years and the trend is continuing. Likewise, developments in storage density, network bandwidth, and compute capacity show similar patterns. As a consequence, the amount of data that can be processed by today's systems has increased by orders of magnitude. At the same time, however, the resolution of screens has hardly increased by a factor of ten. Thus, there is a gap between the amount of data that can be processed and the amount of data that can be visualized. Large high-resolution displays offer a way to deal with this gap and provide a significantly increased screen area by combining the images of multiple smaller display devices. The main objective of this dissertation is the development of new visualization and interaction techniques for large high-resolution displays.