## Fraunhofer (ITWM)

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- numerical upscaling (6)
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- effective heat conductivity (3)
- facility location (3)
- non-Newtonian flow in porous media (3)
- poroelasticity (3)
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- Homogenization for viscoelasticity of the integral type with aging and shrinkage (1998)
- A multi-phase composite with periodic distributed inclusions with a smooth boundary is considered in this contribution. The composite component materials are supposed to be linear viscoelastic and aging (of the non-convolution integral type, for which the Laplace transform with respect to time is not effectively applicable) and are subjected to isotropic shrinkage. The free shrinkage deformation can be considered as a fictitious temperature deformation in the behavior law. The procedure presented in this paper proposes a way to determine average (effective homogenized) viscoelastic and shrinkage (temperature) composite properties and the homogenized stress-field from known properties of the components. This is done by the extension of the asymptotic homogenization technique known for pure elastic non-homogeneous bodies to the non-homogeneous thermo-viscoelasticity of the integral non-convolution type. Up to now, the homogenization theory has not covered viscoelasticity of the integral type. Sanchez-Palencia (1980), Francfort & Suquet (1987) (see [2], [9]) have consid- ered homogenization for viscoelasticity of the differential form and only up to the first derivative order. The integral-modeled viscoelasticity is more general then the differential one and includes almost all known differential models. The homogenization procedure is based on the construction of an asymptotic solution with respect to a period of the composite structure. This reduces the original problem to some auxiliary boundary value problems of elasticity and viscoelasticity on the unit periodic cell, of the same type as the original non-homogeneous problem. The existence and uniqueness results for such problems were obtained for kernels satisfying some constrain conditions. This is done by the extension of the Volterra integral operator theory to the Volterra operators with respect to the time, whose 1 kernels are space linear operators for any fixed time variables. Some ideas of such approach were proposed in [11] and [12], where the Volterra operators with kernels depending additionally on parameter were considered. This manuscript delivers results of the same nature for the case of the space-operator kernels.

- Inverse radiation therapy planning a multiple objective optimisation approach (1999)
- For some decades radiation therapy has been proved successful in cancer treatment. It is the major task of clinical radiation treatment planning to realise on the one hand a high level dose of radiation in the cancer tissue in order to obtain maximum tumour control. On the other hand it is obvious that it is absolutely necessary to keep in the tissue outside the tumour, particularly in organs at risk, the unavoidable radiation as low as possible. No doubt, these two objectives of treatment planning high level dose in the tumour, low radiation outside the tumour have a basically contradictory nature. Therefore, it is no surprise that inverse mathematical models with dose distribution bounds tend to be infeasible in most cases. Thus, there is need for approximations compromising between overdosing the organs at risk and underdosing the target volume. Differing from the currently used time consuming iterative approach, which measures deviation from an ideal (non-achievable) treatment plan using recursively trial-and-error weights for the organs of interest, we go a new way trying to avoid a priori weight choices and consider the treatment planning problem as a multiple objective linear programming problem: with each organ of interest, target tissue as well as organs at risk, we associate an objective function measuring the maximal deviation from the prescribed doses. We build up a data base of relatively few efficient solutions representing and approximating the variety of Pareto solutions of the multiple objective linear programming problem. This data base can be easily scanned by physicians looking for an adequate treatment plan with the aid of an appropriate online tool.

- Considerations about the Estimation of the Size Distribution in Wicksel's Corpuscle Problem (1999)
- Wicksell's corpuscle problem deals with the estimation of the size distribution of a population of particles, all having the same shape, using a lower imensional sampling probe. This problem was originary formulated for particle systems occurring in life sciences but its solution is of actual and increasing interest in materials science. From a mathematical point of view, Wicksell's problem is an inverse problem where the interesting size distribution is the unknown part of a Volterra equation. The problem is often regarded ill-posed, because the structure of the integrand implies unstable numerical solutions. The accuracy of the numerical solutions is considered here using the condition number, which allows to compare different numerical methods with different (equidistant) class sizes and which indicates, as one result, that a finite section thickness of the probe reduces the numerical problems. Furthermore, the relative error of estimation is computed which can be split into two parts. One part consists of the relative discretization error that increases for increasing class size, and the second part is related to the relative statistical error which increases with decreasing class size. For both parts, upper bounds can be given and the sum of them indicates an optimal class width depending on some specific constants.

- Solving nonconvex planar location problems by finite dominating sets (2000)
- It is well-known that some of the classical location problems with polyhedral gauges can be solved in polynomial time by finding a finite dominating set, i.e. a finite set of candidates guaranteed to contain at least one optimal location. In this paper it is first established that this result holds for a much larger class of problems than currently considered in the literature. The model for which this result can be proven includes, for instance, location problems with attraction and repulsion, and location-allocation problems. Next, it is shown that the approximation of general gauges by polyhedral ones in the objective function of our general model can be analyzed with regard to the subsequent error in the optimal objective value. For the approximation problem two different approaches are described, the sandwich procedure and the greedy algorithm. Both of these approaches lead - for fixed epsilon - to polynomial approximation algorithms with accuracy epsilon for solving the general model considered in this paper.

- On the Analysis of Spatial Binary Images (1999)
- This paper deals with the characterization of microscopically heterogeneous, but macroscopically homogeneous spatial structures. A new method is presented which is strictly based on integral-geometric formulae such as Crofton's intersection formulae and Hadwiger's recursive de nition of the Euler number. The corresponding algorithms have clear advantages over other techniques. As an example of application we consider the analysis of spatial digital images produced by means of Computer Assisted Tomo- graphy.

- On the Construction of Discrete Equilibrium Distributions for Kinetic Schemes (1999)
- A general approach to the construction of discrete equilibrium dis- tributions is presented. Such distribution functions can be used to set up Kinetic Schemes as well as Lattice Boltzmann methods. The general principles are also applied to the construction of Chapman Enskog dis- tributions which are used in Kinetic Schemes for compressible Navier Stokes equations.

- A new discrete velocity method for Navier-Stokes equations (1999)
- The relation between the Lattice Boltzmann Method, which has re- cently become popular, and the Kinetic Schemes, which are routinely used in Computational Fluid Dynamics, is explored. A new discrete velocity model for the numerical solution of Navier-Stokes equations for incom- pressible uid ow is presented by combining both the approaches. The new scheme can be interpreted as a pseudo-compressibility method and, for a particular choice of parameters, this interpretation carries over to the Lattice Boltzmann Method.

- On Center Cycles in Grid Graphs (1998)
- Finding "good" cycles in graphs is a problem of great interest in graph theory as well as in locational analysis. We show that the center and median problems are NP hard in general graphs. This result holds both for the variable cardinality case (i.e. all cycles of the graph are considered) and the fixed cardinality case (i.e. only cycles with a given cardinality p are feasible). Hence it is of interest to investigate special cases where the problem is solvable in polynomial time. In grid graphs, the variable cardinality case is, for instance, trivially solvable if the shape of the cycle can be chosen freely. If the shape is fixed to be a rectangle one can analyse rectangles in grid graphs with, in sequence, fixed dimension, fixed cardinality, and variable cardinality. In all cases a com plete characterization of the optimal cycles and closed form expressions of the optimal objective values are given, yielding polynomial time algorithms for all cases of center rectangle problems. Finally, it is shown that center cycles can be chosen as rectangles for small cardinalities such that the center cycle problem in grid graphs is in these cases completely solved.