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A multiscale modeling approach to glioma invasion with therapy

  • We consider the multiscale model for glioma growth introduced in a previous work and extend it to account for therapy effects. Thereby, three treatment strategies involving surgical resection, radio-, and chemotherapy are compared for their efficiency. The chemotherapy relies on inhibiting the binding of cell surface receptors to the surrounding tissue, which impairs both migration and proliferation.

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Author:Alexander Hunt, Christina Surulescu
Document Type:Preprint
Language of publication:English
Publication Date:2015/04/08
Year of Publication:2015
Publishing Institute:Technische Universität Kaiserslautern
Date of the Publication (Server):2015/04/08
Number of page:17
Faculties / Organisational entities:Fachbereich Mathematik
DDC-Cassification:5 Naturwissenschaften und Mathematik / 510 Mathematik
Licence (German):Standard gemäß KLUEDO-Leitlinien vom 13.02.2015