TY - INPR A1 - Zhigun, Anna A1 - Surulescu, Christina A1 - Uatay, Aydar T1 - Global existence for a degenerate haptotaxis model of cancer invasion N2 - We propose and study a strongly coupled PDE-ODE system with tissue-dependent degenerate diffusion and haptotaxis that can serve as a model prototype for cancer cell invasion through the extracellular matrix. We prove the global existence of weak solutions and illustrate the model behaviour by numerical simulations for a two-dimensional setting. KW - cancer cell invasion KW - degenerate diffusion KW - global existence KW - haptotaxis KW - parabolic system KW - weak solution Y1 - 2015 UR - https://kluedo.ub.uni-kl.de/frontdoor/index/index/docId/4232 UR - https://nbn-resolving.org/urn:nbn:de:hbz:386-kluedo-42324 ER -